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Cyclizine hydrochloride
CAS No. 303-25-3
Cyclizine hydrochloride( —— )
Catalog No. M18392 CAS No. 303-25-3
Cyclizine, sold under a number of brand names, is a medication used to treat and prevent nausea, vomiting and dizziness due to motion sickness or vertigo.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | 45 | In Stock |
|
| 200MG | 57 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCyclizine hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionCyclizine, sold under a number of brand names, is a medication used to treat and prevent nausea, vomiting and dizziness due to motion sickness or vertigo.
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DescriptionCyclizine, sold under a number of brand names, is a medication used to treat and prevent nausea, vomiting and dizziness due to motion sickness or vertigo.(In Vitro):Cyclizine (100 μM) significantly inhibits nitrite accumulation and iNOS protein levels in the LPS-stimulated in RAW 264.7 cells supernatants.Cyclizine inhibits anti-IgE-induced histamine release from isolated human lung fragments, with an IC50 of 5.42 μM.(In Vivo):Cyclizine (1, 10 mg/kg) enhances locomotor activity of mice in a dose-dependent manner.
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In VitroCyclizine (100 μM) hydrochloride significantly inhibits nitrite accumulation and iNOS protein levels in the LPS-stimulated in RAW 264.7 cells supernatants.Cyclizine hydrochloride inhibits anti-IgE-induced histamine release from isolated human lung fragments, with an IC50 of 5.42 μM.
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In VivoCyclizine (1-10 mg/kg) hydrochloride enhances locomotor activity of mice in a dose-dependent manner.
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Synonyms——
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PathwayGPCR/G Protein
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TargetNeurokinin Receptor
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RecptorOthers
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number303-25-3
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Formula Weight302.85
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Molecular FormulaC18H22N2·HCl
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Purity>98% (HPLC)
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Solubility——
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SMILESCN1CCN(CC1)C(c1ccccc1)c1ccccc1.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kuntzman, R., et al.: J. Pharmacol. Exp. Ther., 158, 332 (1967).
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